Brahmer 2018 ASCO Table 4.1.1 irAE primary hypothyroidism grade from tsh_miu_l (0.01-150 mIU/L) and three caller-assigned flags. First-match: grade 3 if severe_or_life_threatening or unable_to_perform_adl (paper G3-4 as grade 3); else 2 if moderate_symptoms or TSH >= 10; else 1 if TSH < 10. Returns icpi_action continue (grade 1) or hold_until_baseline (grade 2 or 3). Not hyperthyroidism (Table 4.1.2). magent does not assay TSH/FT4. Not a medical device, not a diagnosis, not a levothyroxine dose.

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