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King's College criteria (O'Grady 1989) for poor prognosis in fulminant hepatic failure. Acetaminophen: arterial pH <7.30, or PT >100 s plus creatinine >300 umol/L plus grade III/IV encephalopathy. Non-acetaminophen: PT >100 s, or any 3 of age <11 or >40, unfavorable etiology (non-A non-B or drug reaction), jaundice-to-encephalopathy >7 days, bilirubin >300 umol/L, PT >50 s. PT seconds, not INR. Not a transplant listing order.

last updated: Oct 6, 2026 · type: http · x402 v2

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