Bello-Chavolla 2018 METS-IR: ln(2×glucose_mg_dl + triglycerides_mg_dl)×BMI / ln(HDL_mg_dl), natural log, two decimals. Supply glucose, triglycerides, and HDL each as exactly one of mg/dL or mmol/L (glucose ×18, TG ×88.57, HDL ×38.67). BMI is caller-supplied (10–80). highest_quartile_t2d is true only when METS-IR > 50.39 (derivation highest T2D-risk quartile). Not a diabetes diagnosis, not HOMA-IR/HOMA2, and not a treatment threshold.

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