Guglielmelli 2018 MIPSS70 for transplant-age PMF: Hb <10 g/dL (1), leukocytes >25×10^9/L (2), platelets <100×10^9/L (2), blasts ≥2% (1), fibrosis ≥2 (1), symptoms (1), no type 1/like CALR (1), HMR category (1), ≥2 HMR (2); max 12. Low 0–1, intermediate 2–4, high ≥5. Italian-cohort median (5-year) OS 27.7 y (95%), 7.1 y (70%), 2.3 y (29%). Not MIPSS70-plus or version 2.0. magent does not sequence or grade marrow.

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