Aziz 2016 Rome IV functional heartburn. rome_iv_heartburn is true iff burning retrosternal discomfort, no relief despite optimal antisecretory therapy, not explained by GERD or eosinophilic esophagitis, no major esophageal motor disorder, last-3-months criteria, and 6-month onset. Caller assigns six flags. magent does not prescribe PPI or read pH-impedance. Not a diagnosis, not globus, not reflux hypersensitivity, not Rome IV IBS.

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